Non-Small Cell Lung Cancer (NSCLC) remains one of the leading causes of cancer-related mortality worldwide. Genetic polymorphisms—particularly single nucleotide polymorphisms (SNPs)—in genes that ...

Taner, M.D., Ph.D., who leads Mayo Clinic's Precision Medicine in Neurodegeneration Lab, studies complex genetic interactions in Alzheimer's disease.

Role of UGT1A1, MTHFR AND TS gene polymorphisms in the prediction of irinotecan (CPT11) and raltitrexed (TOM) gastrointestinal toxicity in pre-treated patients (pts) with metastatic colorectal cancer ...

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis ...

A research team performed a large-scale genome analysis of Japanese and European populations and discovered gene regions (genetic polymorphisms) related to allergic sensitization. Some of these ...

The figure illustrates the major categories of genes that may influence susceptibility to dental caries, organized by their biological functions and pathways. These groups include: (1) Enamel ...

The National Comprehensive Cancer Network lacks specific guidelines for managing lung cancer patients with genetic mutations and little mention of genetic testing (Table 1). Standardizing genetic ...

Breast cancer risk screening using biomarkers and oestrogen metabolism markers could help predict individual risk before starting HRT.

One disease that arises from disruptions in the cell cycle is cancer. After a series of events, a normal cell begins to divide uncontrollably and becomes a tumour cell. Breast tumours are a complex ...