The Hormel Institute, University of Minnesota researchers are looking into how cancer cells respond to treatment with hydroxyurea, a commonly used chemotherapy drug. According to a release from ...
A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...
Attorneys for Matthew Nilo, a New Jersey lawyer prosecutors say they linked to a series of rapes in the North End and Charlestown in the mid-2000s, are asking a judge to suppress key DNA evidence. The ...
CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...
The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...
DNA polymerase delta (Pol δ) is a cornerstone of genomic stability, orchestrating DNA replication and repair through its catalytic subunit, POLD1. This subunit’s 3’–5’ exonuclease domain proofreads ...
SCANDIA, Minn. — The identity of a woman whose remains were found scattered in two Minnesota Lakes in the summer of 1993 is still unknown, despite recent attempts to create a DNA profile. The DNA Doe ...
Human exonuclease 1 (EXO1), a member of the structure-specific nuclease family, plays a critical role in maintaining genome stability by processing DNA double-strand breaks (DSBs), nicks, and ...
This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...
A University of Iowa-led study uncovered a unique double-ring structure of the DNA repair protein RAD52 that plays a critical role in protecting stalled DNA replication in cancer cells with repair ...
A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results